anti- ACSL6 Antibody raised in Rabbit - Cusabio

来自 : 发布时间：2024-04-30

Western Blot analysis of Jurkat cells using ACSL6 Polyclonal Antibody ACSL6 antibody; ACS2 antibody; FACL6 antibody; KIAA0837 antibody; LACS5Long-chain-fatty-acid--CoA ligase 6 antibody; EC 6.2.1.3 antibody; Arachidonate--CoA ligase antibody; EC 6.2.1.15 antibody; Long-chain acyl-CoA synthetase 6 antibody; LACS 6 antibody 纯化方式： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid. ACSL6 drives acyl-CoA toward lipid synthesis and its downregulation improves mitochondrial biogenesis, respiratory capacity and lipid oxidation PMID: 27647415 variations in the ACSL6 gene may contribute to the quantity of cigarettes smoked PMID: 22205969 The alternative fatty acid Gate-domain motifs are essential determinants for the activity of the human ACSL6 isoforms, which appear to act as homodimeric enzyme as well as in complex with other spliced forms. PMID: 20429931 The t(5;12)(q23-31;p13)translocation with ETV6-ACSL6 genomic alteration rearrangement in polycythemia vera patients was reported. PMID: 16572202 Analyses did not yield convincing evidence for associations of schizophrenia with ACSL6 PMID: 16827919 Three ACSL6 spliced variants of a mutually exclusive exon pair are reported, they encode a slightly different short motif which contains a conserved structural domain, the fatty acid Gate domain. PMID: 16834775 haplotypes underlying the SPEC2/PDZ-GEF2/ACSL6 region are associated with schizophrenia PMID: 17030554 The acyl-coenzyme A synthetase long-chain family member 6 (ACSL6) gene on chromosome 5q31 was associated with premature ovarian failure and identified disease-susceptibility haplotypes. PMID: 18555221 ACSL6 is highly associated with schizophrenia and several haplotypes in this haploblock have about twofold to 10-fold increase in the affected subjects in Han Chinese. PMID: 18718982 显示更多 收起更多 相关疾病： A chromosomal aberration involving ACSL6 may be a cause of myelodysplastic syndrome with basophilia. Translocation t(5;12)(q31;p13) with ETV6. 亚细胞定位： Mitochondrion outer membrane, Single-pass type III membrane protein, Peroxisome membrane, Single-pass type III membrane protein, Microsome membrane, Single-pass type III membrane protein, Endoplasmic reticulum membrane, Single-pass type III membrane protein 组织特异性： Expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derived from fetal liver, hemopoietic stem cells from cord blood, bone marrow and brain.