Cusabio/SARS-CoV-2 N Antibody Pair 4/1 pair/CSB-EAP33255A4
商品编号：
CSB-EAP33255A4
品牌：
Cusabio
市场价：
¥20000.00
美元价：
10000.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
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- SARS-CoV-2 N Antibody Pair 4
SARS-CoV-2 N Antibody Pair 4
Datasheet
| Code | CSB-EAP33255A4 |
| Size | US$1000 |
| Image |
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| Have Questions? | Leave a Message or Start an on-line Chat |
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- Target Data
Product Details
| Uniprot No. | P0DTC9 |
| Alternative Names | Nucleocapsid protein, NC, protein N, N |
| Species Reactivity | Human Novel Coronavirus (SARS-CoV-2/ 2019-nCoV) |
| Immunogen | Recombinant Human Novel Coronavirus Nucleoprotein (N) (1-419aa) |
| Immunogen Species | Human Novel Coronavirus (SARS-CoV-2/ 2019-nCoV) |
| Concentration | It differs from different batches. Please contact us to confirm it. |
| Form | Liquid |
| Protein Names | Human Novel Coronavirus Nucleoprotein (N) |
| Host | Capture: MouseDetection: Mouse |
| Buffer | Capture: 50% Glycerol, 0.01M PBS, PH 7.4Detection: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Components | Capture: CSB-EAP33255A4CDetection: CSB-EAP33255A4D(Biotin)Reagents are sufficient for at least 5 x 96 well plates using recommended protocol. |
| Tested Applications | S-ELISA |
| Troubleshooting and FAQs | Antibody FAQs |
| Notes | We recommend using the capture antibody at a concentration of 1ug/ml and the detection antibody at a concentration of 0.05ug/ml. Optimal dilutions should be determined experimentally by the researcher. |
| Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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Target Data
| Function | Nucleoprotein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. It plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Coronavirus nucleoproteins are phosphoproteins, and are encoded near the 3′ end of the genome. N possesses two RNA-binding domains: an N-terminal domain with adjacent S/R-rich motif and the C-terminal 209 amino acids. N protein is invovled in coronavirus infection with many ways: the C-terminal domain (CTD) of N is important for binding the genomic RNA packaging signal leading to selective genome incorporation, the N3 domain interacts with the endodomain of M to form virions, and the serine–arginine repeat region of N (SR) interacts with the first ubiquitin-like domain of nsp3 in a critical early replication step. Moreover, it has also been demonstrated that N can oligomerize through interactions in the CTD, bind viral RNA through the N-terminal domain, unwind double-stranded nucleic acid in the manner of an RNA chaperone, and pack in a helix through the N-terminal domain, though none of these other functions has yet been demonstrated to be important for infection. |
| Subcellular Location | Virion i UniRule annotation, Host endoplasmic reticulum-Golgi intermediate compartment i UniRule annotation, Host Golgi apparatus |
| Protein Families | Betacoronavirus nucleocapsid protein family |
品牌介绍
CUSABIO是一家集研发，生产和销售于一体的国家高科技企业。经过12年的努力，CUSABIO已成为全球研究人员的良好合作伙伴。我们致力于为癌症，细胞生物学，免疫学，神经科学，表观遗传学等研究领域的全球客户提供60,000+种经过验证的抗体，7000 +种重组蛋白，603 +种细胞因子和数千种ELISA试剂盒。我们的所有产品都可以满足客户在各个科研领域的不同需求。
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