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商品详细Cusabio/MYCBP单克隆抗体/100μg/CSB-MA8587101A0m
Cusabio/MYCBP单克隆抗体/100μg/CSB-MA8587101A0m
Cusabio/MYCBP单克隆抗体/100μg/CSB-MA8587101A0m
商品编号: CSB-MA8587101A0m
品牌: Cusabio
市场价: ¥7000.00
美元价: 3500.00
产地: 美国(厂家直采)
公司:
产品分类: 抗体
公司分类: antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

MYCBP Monoclonal Antibody

Datasheet
CodeCSB-MA8587101A0m
SizeUS$350Purchase it in Cusabio online store(only available for customers from the US)
Image
  • Immunohistochemical of paraffin-embedded Human testis tissue using CSB-MA8587101A0m at dilution of 1:200.

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Product Details

Full Product Namemouse anti-Homo sapiens (Human) MYCBP monoclonal antibody
Uniprot No. Q99417
Target NamesMYCBP
Alternative NamesAMY 1 antibody; AMY-1 antibody; AMY1 antibody; Associate of Myc 1 antibody; C myc binding protein antibody; C-Myc-binding protein antibody; Cmyc binding protein antibody; MYCBP antibody; MYCBP_HUMAN antibody
Raised inmouse
Species ReactivityHuman
ImmunogenRecombinant Human MYCBP Protein
Immunogen SpeciesHomo sapiens (Human)
ConjugateNon-conjugated
Clonalitymonoclonal
Clone No.1D5D5
Purification Method>95%,protein G purifed
ConcentrationIt differs from different batches. Please contact us to confirm it.
BufferPreservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Formliquid
Tested ApplicationsELISA,IHC
Recommended Dilution
ApplicationRecommended Dilution
IHC1:50-1:500
ProtocolsELISA ProtocolImmunohistochemistry (IHC) Protocol
Troubleshooting and FAQsAntibody FAQs
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead TimeBasically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Data

FunctionMay control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC.
Gene References into Functions
  1. c-Myc expression is reduced in pterygium compared with normal conjunctiva. PMID: 22050566
  2. Suppression of telomerase activity mediated by PinX1 is involved in the Mad1/c-Myc pathway. PMID: 20544396
  3. miR-22 acts as a tumor suppressor through direct repression of MYCBP expression and subsequent reduction of oncogenic c-Myc activities. PMID: 20562918
  4. identified a novel AMY-1-binding protein, AAT-1, and determied its expression profiles, genes, and cellular localization; results showed that AAT-1 was specifically expressed in the testis throughout spermatogenesis and was also present in mature sperm PMID: 12223483
  5. interacts with S-AKAP84 and AKAP95 in the cytoplasm and the nucleus, respectively, and inhibits enzyme acdtivity by preventing binding of its catalytic subunit to A-kinase-anchoring protein (AKAP) complex PMID: 12414807
  6. AMY-1 coordinates ADP-Ribosylation Factors-mediated membrane trafficking and signaling pathways. PMID: 16866877
  7. An important role for MBP-1 in the altered cell proliferation and energy utilization that occur in response to an altered glucose concentration. PMID: 17595061
  8. AMY-1 was localized in the mitochondria of HeLa and sperm in association with AKAP149 and S-AKAP84, respectively. These results suggest that AMY-1 plays a role in spermatogenesis PMID: 11483602

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Subcellular LocationCytoplasm, Nucleus, Mitochondrion
Protein FamiliesAMY1 family
Tissue SpecificityHighly expressed in heart, placenta, pancreas, skeletal muscle and kidney. Also present at low levels in lung.
Database Links

HGNC: 7554

OMIM: 606535

KEGG: hsa:26292

STRING: 9606.ENSP00000380702

UniGene: Hs.591506

品牌介绍
CUSABIO是一家集研发,生产和销售于一体的国家高科技企业。经过12年的努力,CUSABIO已成为全球研究人员的良好合作伙伴。我们致力于为癌症,细胞生物学,免疫学,神经科学,表观遗传学等研究领域的全球客户提供60,000+种经过验证的抗体,7000 +种重组蛋白,603 +种细胞因子和数千种ELISA试剂盒。我们的所有产品都可以满足客户在各个科研领域的不同需求。