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商品详细Cusabio/N抗体/100ul/CSB-PA33255A0Rb
Cusabio/N抗体/100ul/CSB-PA33255A0Rb
Cusabio/N抗体/100ul/CSB-PA33255A0Rb
商品编号: CSB-PA33255A0Rb
品牌: Cusabio
市场价: ¥0.00
美元价: 0.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

N Antibody

Datasheet
CodeCSB-PA33255A0Rb
Size
Image
  • The Binding Activity of SARS-CoV-2-N Antibody with SARS-CoV-2-NActivity: Measured by its binding ability in a functional ELISA. Immobilized SARS-CoV-2-N (CSB-EP3325GMY) at 2 μg/ml can bind SARS-CoV-2-N Antibody, the EC50 is 1.586 ng/ml.
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Product Details

Full Product NameRabbit anti-Human Novel Coronavirus (SARS-CoV-2/ 2019-nCoV) N Polyclonal antibody
Uniprot No.P0DTC9
Target NamesN
Alternative NamesNucleocapsid protein, NC, protein N, N
Raised inRabbit
Species ReactivityHuman Novel Coronavirus (SARS-CoV-2/ 2019-nCoV)
ImmunogenRecombinant Human Novel Coronavirus Nucleoprotein (N) (1-419aa) (CSB-EP3325GMY)
Immunogen SpeciesHuman Novel Coronavirus (SARS-CoV-2/ 2019-nCoV)
ConjugateNon-conjugated
ClonalityPolyclonal
IsotypeIgG
Purification Method>95%, Protein G purified
ConcentrationIt differs from different batches. Please contact us to confirm it.
BufferPreservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
FormLiquid
Tested ApplicationsELISA
Recommended Dilution
ApplicationRecommended Dilution
ELISA1:1000-1:5000
ProtocolsELISA Protocol
Troubleshooting and FAQsAntibody FAQs
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead TimeBasically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Data

FunctionNucleoprotein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. It plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Coronavirus nucleoproteins are phosphoproteins, and are encoded near the 3′ end of the genome. N possesses two RNA-binding domains: an N-terminal domain with adjacent S/R-rich motif and the C-terminal 209 amino acids. N protein is invovled in coronavirus infection with many ways: the C-terminal domain (CTD) of N is important for binding the genomic RNA packaging signal leading to selective genome incorporation, the N3 domain interacts with the endodomain of M to form virions, and the serine–arginine repeat region of N (SR) interacts with the first ubiquitin-like domain of nsp3 in a critical early replication step. Moreover, it has also been demonstrated that N can oligomerize through interactions in the CTD, bind viral RNA through the N-terminal domain, unwind double-stranded nucleic acid in the manner of an RNA chaperone, and pack in a helix through the N-terminal domain, though none of these other functions has yet been demonstrated to be important for infection.
Subcellular LocationVirion i UniRule annotation, Host endoplasmic reticulum-Golgi intermediate compartment i UniRule annotation, Host Golgi apparatus
Protein FamiliesBetacoronavirus nucleocapsid protein family
品牌介绍
CUSABIO是一家集研发,生产和销售于一体的国家高科技企业。经过12年的努力,CUSABIO已成为全球研究人员的良好合作伙伴。我们致力于为癌症,细胞生物学,免疫学,神经科学,表观遗传学等研究领域的全球客户提供60,000+种经过验证的抗体,7000 +种重组蛋白,603 +种细胞因子和数千种ELISA试剂盒。我们的所有产品都可以满足客户在各个科研领域的不同需求。