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当前位置: 首页 > 产品中心 > Crosslinkers > Cusabio/重组人5-羟色胺受体1F(HTR1F)/100μg/CSB-CF010886HU
商品详细Cusabio/重组人5-羟色胺受体1F(HTR1F)/100μg/CSB-CF010886HU
Cusabio/重组人5-羟色胺受体1F(HTR1F)/100μg/CSB-CF010886HU
Cusabio/重组人5-羟色胺受体1F(HTR1F)/100μg/CSB-CF010886HU
商品编号: CSB-CF010886HU
品牌: Cusabio
市场价: ¥69800.00
美元价: 34900.00
产地: 美国(厂家直采)
公司:
产品分类: 蛋白交联剂
公司分类: Crosslinkers
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Recombinant Human 5-hydroxytryptamine receptor 1F(HTR1F)

In Stock
CodeCSB-CF010886HU
SizeUS$3490Purchase it in Cusabio online store(only available for customers from the US)
Image
  • SDS-PAGE- Recombinant protein Human HTR1F

    (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

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Product Details

PurityGreater than 85% as determined by SDS-PAGE.
Target NamesHTR1F
Uniprot No.P30939
Research AreaMetabolism
Alternative NamesHTR1F; HTR1EL5-hydroxytryptamine receptor 1F; 5-HT-1F; 5-HT1F; Serotonin receptor 1F
SpeciesHomo sapiens (Human)
Sourcein vitro E.coli expression system
Expression Region1-366aa
Target Protein SequenceMDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIVSTIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKSVSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCRCNote: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
Mol. Weight60.2 kDa
Protein LengthFull Length
Tag InfoN-terminal 10xHis-SUMO-tagged
FormLiquid or Lyophilized powder Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.Note: If you have any special requirement for the glycerol content, please remark when you place the order.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
ReconstitutionWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQsProtein FAQs
Storage ConditionStore at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf LifeThe shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead TimeBasically, we can dispatch the products out in 3-7 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
NotesRepeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA Please contact us to get it.

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Target Data

FunctionG-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
Gene References into Functions
  1. Supporting this model, pharmacological activation of 5-HT1F receptors reduces glucagon secretion and has hypoglycemic effects in diabetic mice. Thus, modulation of serotonin signaling in the islet represents a drug intervention opportunity PMID: 28009296
  2. 5-HT6 show no striking effects on executive function in the Chinese Han population. PMID: 21457069
Subcellular LocationCell membrane, Multi-pass membrane protein
Protein FamiliesG-protein coupled receptor 1 family
Database Links

HGNC: 5292

OMIM: 182134

KEGG: hsa:3355

STRING: 9606.ENSP00000322924

UniGene: Hs.248136

品牌介绍
CUSABIO是一家集研发,生产和销售于一体的国家高科技企业。经过12年的努力,CUSABIO已成为全球研究人员的良好合作伙伴。我们致力于为癌症,细胞生物学,免疫学,神经科学,表观遗传学等研究领域的全球客户提供60,000+种经过验证的抗体,7000 +种重组蛋白,603 +种细胞因子和数千种ELISA试剂盒。我们的所有产品都可以满足客户在各个科研领域的不同需求。