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当前位置: 首页 > 产品中心 > ultrafiltration > Cusabio/重组马白细胞介素-1受体拮抗蛋白(IL1RN)(活性)/1mg/CSB-AP003491HO
商品详细Cusabio/重组马白细胞介素-1受体拮抗蛋白(IL1RN)(活性)/1mg/CSB-AP003491HO
Cusabio/重组马白细胞介素-1受体拮抗蛋白(IL1RN)(活性)/1mg/CSB-AP003491HO
Cusabio/重组马白细胞介素-1受体拮抗蛋白(IL1RN)(活性)/1mg/CSB-AP003491HO
商品编号: CSB-AP003491HO
品牌: Cusabio
市场价: ¥47820.00
美元价: 23910.00
产地: 美国(厂家直采)
公司:
产品分类: 超滤
公司分类: ultrafiltration
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Recombinant Horse Interleukin-1 Receptor Antagonist protein(IL1RN) (Active)

In Stock
CodeCSB-AP003491HO
SizeUS$2391Purchase it in Cusabio online store(only available for customers from the US)
Image
  • SDS-PAGE- Recombinant protein Horse IL1RN
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Product Details

Purity>95% as determined by SDS-PAGE and HPLC.
EndotoxinLess than 1.0 EU/μg as determined by LAL method.
ActivityFully biologically active when compared to standard. The ED50 as determined by inhibiting IL-1α- dependent proliferation of murine D10S cells is less than 3.0 μg/ml, corresponding to a specific activity of >333 IU/mg in the presence of 50 pg/ml rHuIL-1α.
Target NamesIL1RN
Uniprot No.O18999
Research AreaImmunology
Alternative NamesIL1RN; IL1RAInterleukin-1 receptor antagonist protein; IL-1RN; IL-1ra; IRAP; IL1 inhibitor
SpeciesEquus caballus (Horse)
SourceE.coli
Expression Region26-177aa
Complete SequenceHPLGKRPCKM QAFRIWDVNQ KTFYMRNNQL VAGYLQESNT KLQEKIDVVP IEPDALFLGL HGRKLCLACV KSGDEIRFQL EAVNITDLSK NKEENKRFTF IRSNSGPTTS FESAACPGWF LCTAQEADRP VSLTNKPKES FMVTKFYLQE DQ
Mol. Weight17.4 kDa
Protein LengthFull Length of Mature Protein
Tag InfoTag-Free
FormLyophilized powder
BufferLyophilized from a0.2 µm filteredPBS, pH 7.4
ReconstitutionWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQsProtein FAQs
Storage ConditionStore at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf LifeThe shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead TimeBasically, we can dispatch the products out in 5-10 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
NotesRepeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA Please contact us to get it.

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Target Data

FunctionInhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity.
Gene References into Functions
  1. This is the first study in an equine model to establish a dosing/redosing protocol, as well as examine the Nab response to capsid and supports further clinical investigation to determine the clinical efficacy of scAAVIL-1ra to treat osteoarthritis. PMID: 25902762
  2. Expression of IL-1RN in the endometrium is likely regulated by estradiol and progesterone and suggest that IL-1RN regulates the degree of IL-1 signal transduction and thereby plays an important role in the establishment of equine pregnancy. PMID: 19157767
Subcellular LocationSecreted
Protein FamiliesIL-1 family
Database Links

KEGG: ecb:100034236

STRING: 9796.ENSECAP00000004056

UniGene: Eca.13123

品牌介绍
CUSABIO是一家集研发,生产和销售于一体的国家高科技企业。经过12年的努力,CUSABIO已成为全球研究人员的良好合作伙伴。我们致力于为癌症,细胞生物学,免疫学,神经科学,表观遗传学等研究领域的全球客户提供60,000+种经过验证的抗体,7000 +种重组蛋白,603 +种细胞因子和数千种ELISA试剂盒。我们的所有产品都可以满足客户在各个科研领域的不同需求。