Cusabio/人中性粒细胞明胶酶相关脂质转运蛋白/1g/CSB-NP068341h
商品编号：
CSB-NP068341h
品牌：
Cusabio
市场价：
¥0.00
美元价：
0.00
产品分类：
蛋白纯化试剂盒
公司分类：
Protein_purification_kit
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Specification
| Code | CSB-NP068341h |
| Product Type | Native Protein |
| Size | US$173335Purchase it in Cusabio online store(Shop online in the US.Customers outside the US, please order from local distributors.) |
| Relevance | Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2, 5-dihydroxybenzoic acid (2, 5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. Involved in innate immunity, possibly by sequestrating iron, leading to limit bacterial growth. |
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| Tested Applications | ELISA, WB, SDS-PAGE. Latex enhanced turbidimetric immunoassay (LETIA), immunogen and other possible |
| Form | Liquid |
| Storage Buffer | PBS, pH 7.4 |
| Alias | N/A |
| Biological_Activity | Not test |
| Purity | >95% (SDS-PAGE) |
| Sequence | Full length protein |
| Research Area | Immunology |
| Source | Purified from Human urine |
| Protein Names | Human Neutrophil gelatinase-associated lipocalin protein |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Still Have Questions? |
品牌介绍
CUSABIO是一家集研发，生产和销售于一体的国家高科技企业。经过12年的努力，CUSABIO已成为全球研究人员的良好合作伙伴。我们致力于为癌症，细胞生物学，免疫学，神经科学，表观遗传学等研究领域的全球客户提供60,000+种经过验证的抗体，7000 +种重组蛋白，603 +种细胞因子和数千种ELISA试剂盒。我们的所有产品都可以满足客户在各个科研领域的不同需求。
联络我们
总部地址：
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工作时间：周一至周五9:00~18:00
技术支持：
短信：18915418616
服务热线：
4000-520-616（全国）
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